Another approach would be to use a plant that shifts adrenal metabolism away from cortisol to adrenal androgens, such as Sequoia gigantea GM.ģβ-Hydroxysteroid dehydrogenase type II isoenzyme (3β-HSD2) In addition, you may add a plant with adrenal androgenic activity such as Rosa canina. If appropriate, reduce cortisol activity by inhibiting alpha and/or ACTH. For example, if the cortisol index is absolutely elevated and the adrenal cortex index is low it suggests an insufficiency of adrenal androgens in relationship to cortisol. When selecting medicinal plants to balance the activity of the adrenal cortex, look at the relationship of the cortisol index to the adrenal cortex index. Clinical pearl: Balancing adrenal cortex activity Adaptive functions include production of cortisol, cell nutrition, vigilance and memory. Permissive functions of the adrenal cortex include production of anabolic steroids, and cell metabolism.
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